- Vaginal cancer is rare. It accounts for 1% to 2% of cancers in the female genital tract, and a very small portion of cancers overall.
- Approximately 18,000 new cases of vaginal cancer were reported worldwide in 2020 and 8,000 women died from the disease.
- Infection with human papillomavirus (HPV) causes two-thirds of the cases of vaginal cancer. Vaccines that protect against infection with HPV may reduce the risk of vaginal cancer.
- Vaginal cancer most commonly affects postmenopausal women aged 50 and older.